BCAM

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BCAM mutation is significantly associated with the RNA expression of many other genes, with 1,352 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCAM-associated genes across cancer lineages are MIR449B, RNA5SP192, and EMX2OS. Each is linked with BCAM in more than 2 cancer types. Because this analysis shows association rather than direction, both BCAM-to-partner and partner-to-BCAM results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAM→partner) and Y-score (partner→BCAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCMIR449B →+0.453+7.954<.001.00833
SKCMRNA5SP192 →+0.052+3.369<.001.00232
UCECEMX2OS →-0.967-1.847.004.00932
UCECRN7SL248P →+0.053+2.985<.001.00632
UCECMIR7702 →+0.155+3.668<.001.00932
UCECAOC2 →+0.962+2.423<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,352 associations by consensus.

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