BBS4

Across TCGA patient cohorts, BBS4 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,252 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BBS4-associated proteins across cancer lineages are ANP32A, HDGFL3, and TP53BP1. Each is linked with BBS4 in more than 5 cancer types. Because this analysis shows association rather than direction, both BBS4-to-partner and partner-to-BBS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BBS4 versus ANP32A in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BBS4→partner) and Y-score (partner→BBS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ANP32A →	+0.383	+0.436	<.001	<.001	3	6
BRCA	HDGFL3 →	+0.808	+0.854	<.001	<.001	3	6
BRCA	TP53BP1 →	+0.354	+0.890	<.001	<.001	3	5
GBM	CEP164_S359 →	+0.563	+0.268	<.001	.006	3	5
PDAC	HCCS →	-0.338	-0.349	<.001	<.001	3	5
LSCC	MYEF2 →	+0.904	+0.397	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,252 associations by consensus.

BBS4 vs ANP32A — LSCC

Explore this scatter interactively →