BBS4

Across TCGA patient cohorts, BBS4 protein abundance is significantly associated with the RNA expression of many other genes, with 11,691 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BBS4-associated genes across cancer lineages are KIF14, MDH1B, and DNAI4. Each is linked with BBS4 in more than 5 cancer types. Because this analysis shows association rather than direction, both BBS4-to-partner and partner-to-BBS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BBS4 versus KIF14 in LUAD, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BBS4→partner) and Y-score (partner→BBS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KIF14 →	-0.879	-0.284	.001	.003	3	6
BRCA	MDH1B →	+1.123	+0.492	<.001	<.001	3	6
UCEC	DNAI4 →	+1.054	+0.414	<.001	<.001	3	6
BRCA	CKAP2L →	-1.066	-0.415	<.001	<.001	3	6
UCEC	PIFO →	+1.717	+0.438	<.001	<.001	3	6
GBM	HASPIN →	-0.721	-0.299	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,691 associations by consensus.

BBS4 vs KIF14 — LUAD

Explore this scatter interactively →