BBS2

Across TCGA patient cohorts, BBS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,964 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BBS2-associated proteins across cancer lineages are DDX21_S89, DDX21_S71, and THEMIS2. Each is linked with BBS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both BBS2-to-partner and partner-to-BBS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BBS2 versus DDX21_S89 in BRCA, with a Pearson correlation of -0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BBS2→partner) and Y-score (partner→BBS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DDX21_S89 →	-0.805	-0.517	<.001	<.001	3	7
GBM	DDX21_S71 →	-1.067	-0.774	.001	<.001	3	6
GBM	THEMIS2 →	-0.492	-0.508	<.001	<.001	3	5
GBM	PDPR →	+0.293	+0.498	.004	<.001	3	5
UCEC	NCL_S67 →	-0.679	-0.528	.001	.007	3	5
HNSC	SLC38A1_S49 →	-0.823	-0.684	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,964 associations by consensus.

BBS2 vs DDX21_S89 — BRCA

Explore this scatter interactively →