BBS2

Across TCGA patient cohorts, BBS2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,218 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BBS2-associated genes across cancer lineages are CEP55, EFCAB6, and CEP126. Each is linked with BBS2 in more than 7 cancer types. Because this analysis shows association rather than direction, both BBS2-to-partner and partner-to-BBS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BBS2 versus CEP55 in UCEC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BBS2→partner) and Y-score (partner→BBS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CEP55 →	-1.056	-0.507	<.001	<.001	3	8
UCEC	EFCAB6 →	+1.076	+0.492	<.001	<.001	3	8
UCEC	CEP126 →	+1.079	+0.484	<.001	<.001	3	7
UCEC	CCDC89 →	+0.774	+0.424	<.001	<.001	3	7
UCEC	BBS12 →	+0.594	+0.522	.001	<.001	3	7
UCEC	PRKN →	+0.555	+0.400	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,218 associations by consensus.

BBS2 vs CEP55 — UCEC

Explore this scatter interactively →