BBS2

Across TCGA patient cohorts, BBS2 protein abundance is significantly associated with the protein abundance of many other proteins, with 22,248 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BBS2-associated proteins across cancer lineages are SEPTIN2, DDX21, and BAZ1A. Each is linked with BBS2 in more than 7 cancer types. Because this analysis shows association rather than direction, both BBS2-to-partner and partner-to-BBS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BBS2 versus SEPTIN2 in UCEC, with a Pearson correlation of 0.44.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BBS2→partner) and Y-score (partner→BBS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SEPTIN2 →	+0.298	+0.584	<.001	<.001	3	8
BRCA	DDX21 →	-0.654	-0.503	<.001	<.001	3	8
GBM	BAZ1A →	-0.445	-0.283	<.001	<.001	3	7
UCEC	SEPTIN11 →	+0.340	+0.285	<.001	.002	3	7
BRCA	TLN2 →	+0.661	+0.610	<.001	<.001	3	7
BRCA	TNS2_S120 →	+0.725	+0.559	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,248 associations by consensus.

BBS2 vs SEPTIN2 — UCEC

Explore this scatter interactively →