BBS2

Across TCGA cell cohorts, BBS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,835 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BBS2-associated GO terms across cancer lineages are Transport along microtubule, Cytoskeleton-dependent intracellular transport, and Negative regulation of myoblast fusion. Each is linked with BBS2 in more than 15 cancer types. Because this analysis shows association rather than direction, both BBS2-to-partner and partner-to-BBS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport along microtubule grouped by BBS2-low versus BBS2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BBS2→partner) and Y-score (partner→BBS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Transport along microtubule →	+0.070	+0.866	<.001	<.001	3	16
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.049	+0.619	<.001	<.001	3	16
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.151	+1.107	.005	.006	3	15
UPPER_AERODIGESTIVE_TRACT	Autophagy →	+0.056	+0.931	.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Process utilizing autophagic mechanism →	+0.056	+0.931	.001	.001	3	14
LARGE_INTESTINE	Regulation of organelle assembly →	+0.047	+0.937	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,835 associations by consensus.

Transport along microtubule by BBS2 expression — LUNG_SCLC

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