BBOX1-AS1

Across TCGA pan-cancer cohorts, BBOX1-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated BBOX1-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher BBOX1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BBOX1-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and UCS show a favorable association.

MESO, KIRC, and LGG are the cancer types where BBOX1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Quartile	All	0.248	0.559	<.001	98	view →
KIRC	OS	Tertile	II,III,IV	0.411	0.634	.002	78	view →
LGG	DFS	Tertile	All	0.311	0.564	<.001	47	view →
KIRP	OS	Tertile	All	0.897	0.982	.003	34	view →
BRCA	DFS	Median	IV	0.805	0.339	.002	30	view →
UCEC	DFS	Quartile	All	0.784	0.904	.004	30	view →
COAD	OS	Quartile	All	0.655	0.890	.001	25	view →
UCS	DFS	Median	II,III,IV	0.601	0.279	.007	20	view →
READ	OS	Quartile	III,IV	0.956	0.727	.009	20	view →
LIHC	DFS	Tertile	All	0.483	0.603	.014	16	view →
THCA	OS	Tertile	All	0.994	0.889	.009	12	view →
DLBC	OS	Median	All	0.794	1.000	.004	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

BBOX1-AS1–MESO (OS)

Open the MESO breakdown →