BBOF1

Across TCGA patient cohorts, BBOF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,873 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BBOF1-associated proteins across cancer lineages are DNAL1, WDR54, and IFT46. Each is linked with BBOF1 in more than 6 cancer types. Because this analysis shows association rather than direction, both BBOF1-to-partner and partner-to-BBOF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BBOF1 versus DNAL1 in BRCA, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BBOF1→partner) and Y-score (partner→BBOF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DNAL1 →	+0.499	+1.178	<.001	<.001	3	7
UCEC	WDR54 →	+0.443	+0.981	<.001	<.001	3	7
BRCA	IFT46 →	+0.471	+0.944	<.001	<.001	3	6
BRCA	BBS2 →	+0.494	+0.873	<.001	<.001	3	6
BRCA	WDR19 →	+0.481	+1.319	<.001	<.001	3	6
UCEC	WDR35 →	+0.387	+1.008	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,873 associations by consensus.

BBOF1 vs DNAL1 — BRCA

Explore this scatter interactively →