BBOF1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BBOF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,837 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BBOF1-associated GO terms across cancer lineages are Autophagosome organization, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Autophagosome assembly. Each is linked with BBOF1 in more than 14 cancer types. Because this analysis shows association rather than direction, both BBOF1-to-partner and partner-to-BBOF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagosome organization grouped by BBOF1-low versus BBOF1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BBOF1→partner) and Y-score (partner→BBOF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaAutophagosome organization →+0.068+0.917.001.002315
OESOPHAGUSEndoplasmic reticulum to Golgi vesicle-mediated transport →+0.093+0.915.004.001314
BLOOD_MyelomaAutophagosome assembly →+0.071+1.097.003.002314
SOFT_TISSUEProcess utilizing autophagic mechanism →+0.049+0.827<.001<.001314
SOFT_TISSUEAutophagy →+0.049+0.827<.001<.001314
UPPER_AERODIGESTIVE_TRACTMacroautophagy →+0.058+0.764.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,837 associations by consensus.

Autophagosome organization by BBOF1 expression — BLOOD_Myeloma

Box plot of Autophagosome organization in BBOF1-low vs BBOF1-high samples in BLOOD_Myeloma.

Explore this box plot interactively →

Exploration