BAZ2B

Across TCGA patient cohorts, BAZ2B mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAZ2B-associated genes across cancer lineages are Akt_pT308, ATM, and YAP_pS127. Each is linked with BAZ2B in more than 3 cancer types. Because this analysis shows association rather than direction, both BAZ2B-to-partner and partner-to-BAZ2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Akt_pT308 grouped by BAZ2B-low versus BAZ2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAZ2B→partner) and Y-score (partner→BAZ2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Akt_pT308 →	+0.418	+1.192	.013	.007	3	4
UCEC	ATM →	-0.421	-1.192	<.001	.007	3	4
STAD	YAP_pS127 →	-0.370	-2.321	.011	.034	3	3
SKCM	c-Kit →	-0.536	-2.321	.025	.033	3	3
UCEC	Akt_pS473 →	+0.447	+0.906	.019	.041	3	3
UCEC	4E-BP1 →	+0.226	+1.502	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

Akt_pT308 by BAZ2B expression — UCEC

Explore this box plot interactively →