BAZ2B

Across TCGA pan-cancer cohorts, BAZ2B RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of BAZ2B’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where BAZ2B RNA is repressed in tumor relative to normal tissue. In most cancer types BAZ2B is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KICH, UCEC, and LUSC are the cancer types where BAZ2B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BAZ2B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−1.217	<.001	8	view →
UCEC	All	All	−0.664	<.001	6	view →
LUSC	Male	All	−0.382	<.001	6	view →
BRCA	Female	All	−0.379	<.001	6	view →
CHOL	All	All	+1.161	<.001	3	view →
KIRC	Male	III,IV	−0.379	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

BAZ2B–KICH

Open the KICH breakdown →