BAZ2B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BAZ2B mutation is significantly associated with the RNA expression of many other genes, with 458 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BAZ2B-associated genes across cancer lineages are ENTHD1, TLCD3A, and RSC1A1. Each is linked with BAZ2B in more than 2 cancer types. Because this analysis shows association rather than direction, both BAZ2B-to-partner and partner-to-BAZ2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ENTHD1 grouped by BAZ2B-low versus BAZ2B-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAZ2B→partner) and Y-score (partner→BAZ2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCENTHD1 →+0.132+3.220.004.00233
LARGE_INTESTINETLCD3A →+0.519+2.459.007.00633
LARGE_INTESTINERSC1A1 →+0.681+1.712<.001.00433
BLOOD_MyelomaLRRC74A →+0.013+4.807<.001.00632
BLOOD_MyelomaOR2AJ1 →+0.013+4.807<.001.00632
PANCREASZNF479 →+0.011+3.139<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 458 associations by consensus.

ENTHD1 by BAZ2B expression — LUNG_SCLC

Box plot of ENTHD1 in BAZ2B-low vs BAZ2B-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration