BAX

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BAX RNA expression is significantly associated with the protein abundance of many other proteins, with 8,345 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible BAX-associated proteins across cancer lineages are CDKN1B, GOLGA2_S981, and MCM2_S139. Each is linked with BAX in more than 3 cancer types. Because this analysis shows association rather than direction, both BAX-to-partner and partner-to-BAX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BAX versus CDKN1B in LSCC, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BAX→partner) and Y-score (partner→BAX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCDKN1B →-0.315-0.316.004.00234
PDACGOLGA2_S981 →+0.839+0.291.003.00133
BRCAMCM2_S139 →+0.575+0.474<.001.00333
PDACPAIP2B →-0.624-0.249.007.00833
BRCAPRKAR2A →-0.216-0.441.001.00233
BRCAGORASP2 →-0.217-0.718.002<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,345 associations by consensus.

BAX vs CDKN1B — LSCC

Per-sample scatter of BAX vs CDKN1B in LSCC (Pearson r = -0.27).

Explore this scatter interactively →

Exploration