BAX

Across TCGA patient cohorts, BAX protein abundance is significantly associated with the RNA expression of many other genes, with 12,419 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BAX-associated genes across cancer lineages are RUBCNL, NUCB1, and SLC35D1. Each is linked with BAX in more than 4 cancer types. Because this analysis shows association rather than direction, both BAX-to-partner and partner-to-BAX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BAX versus RUBCNL in HNSC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAX→partner) and Y-score (partner→BAX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RUBCNL →	+0.790	+0.298	<.001	<.001	3	5
OV	NUCB1 →	+0.555	+0.243	<.001	<.001	3	4
OV	SLC35D1 →	+0.897	+0.360	<.001	<.001	3	4
OV	ZNF543 →	+0.437	+0.212	.005	<.001	3	4
COAD	RPS27L →	+0.580	+0.182	.001	.003	3	4
CCRCC	BAIAP2L2 →	-0.795	-0.157	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,419 associations by consensus.

BAX vs RUBCNL — HNSC

Explore this scatter interactively →