BAX

Across TCGA patient cohorts, BAX mutation is significantly associated with the RNA expression of many other genes, with 199 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAX-associated genes across cancer lineages are RNU6-618P, RNA5SP473, and RNU2-61P. Each is linked with BAX in more than 1 cancer types. Because this analysis shows association rather than direction, both BAX-to-partner and partner-to-BAX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-618P grouped by BAX-low versus BAX-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAX→partner) and Y-score (partner→BAX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-618P →	+0.349	+3.767	<.001	.003	3	2
UCEC	RNA5SP473 →	+0.668	+3.226	.004	<.001	3	2
LUAD	RNU2-61P →	+0.912	+5.315	<.001	.003	3	2
LIHC	RN7SL718P →	+0.161	+4.758	<.001	.006	3	1
CESC	MTND5P23 →	+0.021	+5.539	<.001	.004	3	1
CESC	RN7SL551P →	+0.107	+5.969	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 199 associations by consensus.

RNU6-618P by BAX expression — SKCM

Explore this box plot interactively →