BASP1

Across TCGA patient cohorts, BASP1 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BASP1-associated genes across cancer lineages are TFRC, cIAP, and JNK2. Each is linked with BASP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BASP1-to-partner and partner-to-BASP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by BASP1-low versus BASP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BASP1→partner) and Y-score (partner→BASP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TFRC →	+0.578	+2.195	.021	.034	3	2
COAD	cIAP →	+0.131	+2.229	.029	.032	3	2
UCEC	JNK2 →	+0.207	+2.817	.017	.036	3	2
UCEC	PCNA →	+0.274	+3.169	.003	.018	3	2
UCEC	Cyclin-B1 →	+0.691	+3.169	.004	.018	3	2
COAD	SLC1A5 →	+0.574	+3.169	.006	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

TFRC by BASP1 expression — COAD

Explore this box plot interactively →