BASP1

Across TCGA pan-cancer cohorts, BASP1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of BASP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where BASP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BASP1 is over-expressed in tumor, although a few such as LIHC and KICH show the opposite, repressed pattern.

HNSC, THCA, and LUAD are the cancer types where BASP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BASP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	IV	+2.815	<.001	12	view →
THCA	Male	III,IV	+2.142	<.001	10	view →
LUAD	All	III,IV	+1.759	<.001	9	view →
KIRC	Male	All	+0.790	<.001	7	view →
UCEC	All	All	+1.838	<.001	6	view →
BRCA	Female	II,III,IV	+1.175	<.001	6	view →
LUSC	Female	All	+1.944	<.001	5	view →
LIHC	Male	All	−1.439	<.001	5	view →
CHOL	All	All	+1.543	.018	2	view →
KICH	All	II,III,IV	−1.205	.018	2	view →
COAD	All	All	−0.494	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

BASP1–HNSC

Open the HNSC breakdown →