BARX2

Across TCGA patient cohorts, BARX2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,717 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BARX2-associated genes across cancer lineages are PRODH, SAMM50, and ABHD4. Each is linked with BARX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BARX2-to-partner and partner-to-BARX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BARX2 versus PRODH in BRCA, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BARX2→partner) and Y-score (partner→BARX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PRODH →	-1.218	-0.797	<.001	<.001	3	1
BRCA	SAMM50 →	-0.527	-0.834	.001	.003	3	1
BRCA	ABHD4 →	-1.015	-0.844	<.001	.007	3	1
BRCA	SPTLC2 →	-0.820	-1.033	.009	.002	3	1
BRCA	VRK1 →	+0.570	+0.776	.005	.001	3	1
BRCA	SCML2 →	+1.048	+0.659	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,717 associations by consensus.

BARX2 vs PRODH — BRCA

Explore this scatter interactively →