BARX2

Across TCGA patient cohorts, BARX2 mutation is significantly associated with the RNA expression of many other genes, with 92 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible BARX2-associated genes across cancer lineages are RNA5SP427, DPP9, and ANKRD26P2. Each is linked with BARX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BARX2-to-partner and partner-to-BARX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP427 grouped by BARX2-low versus BARX2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BARX2→partner) and Y-score (partner→BARX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP427 →	+0.592	+5.103	<.001	.008	3	2
SKCM	DPP9 →	+0.367	+2.536	.003	.009	3	2
BLCA	ANKRD26P2 →	+0.037	+5.411	<.001	.005	3	2
LUSC	SNORA70I →	+0.274	+5.093	.001	.008	3	1
LUSC	LINC02514 →	+0.157	+5.978	.002	.002	3	1
UCEC	ATP6V1E1P2 →	+0.204	+3.077	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 92 associations by consensus.

RNA5SP427 by BARX2 expression — CESC

Explore this box plot interactively →