BARX2

Across TCGA patient cohorts, BARX2 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible BARX2-associated genes across cancer lineages are GAPDH, 4E-BP1_pT70, and AMPK_pT172. Each is linked with BARX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BARX2-to-partner and partner-to-BARX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by BARX2-low versus BARX2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BARX2→partner) and Y-score (partner→BARX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GAPDH →	+0.661	+2.321	.023	.035	3	1
SKCM	4E-BP1_pT70 →	-0.222	-2.304	.013	.035	3	1
SKCM	AMPK_pT172 →	+0.351	+2.321	.032	.035	2	1
SKCM	beta-Catenin →	-0.552	-2.321	.032	.035	2	1
SKCM	ERK2 →	+0.223	+2.321	.034	.035	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

GAPDH by BARX2 expression — SKCM

Explore this box plot interactively →