BARX2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BARX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,375 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible BARX2-associated GO terms across cancer lineages are Regulation of keratinocyte apoptotic process, Regulation of hair cycle, and Mammary gland morphogenesis. Each is linked with BARX2 in more than 7 cancer types. Because this analysis shows association rather than direction, both BARX2-to-partner and partner-to-BARX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of keratinocyte apoptotic process grouped by BARX2-low versus BARX2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BARX2→partner) and Y-score (partner→BARX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTRegulation of keratinocyte apoptotic process →+0.133+1.484.007.00538
SKINRegulation of hair cycle →+0.129+1.185<.001.00537
LUNG_NSCLC_LUSCMammary gland morphogenesis →+0.166+1.867.003.00337
PANCREASNMDA selective glutamate receptor signaling pathway →+0.162+1.824<.001.00137
OVARYRegulation of gastro-intestinal system smooth muscle contraction →+1.278+1.341<.001.00337
OVARYPositive regulation of gastro-intestinal system smooth muscle contraction →+1.278+1.341<.001.00337
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,375 associations by consensus.

Regulation of keratinocyte apoptotic process by BARX2 expression — URINARY_TRACT

Box plot of Regulation of keratinocyte apoptotic process in BARX2-low vs BARX2-high samples in URINARY_TRACT.

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