BARX2

Across TCGA cell cohorts, BARX2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BARX2-associated genes across cancer lineages are C20orf85, IL22, and TRIM60. Each is linked with BARX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BARX2-to-partner and partner-to-BARX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C20orf85 grouped by BARX2-low versus BARX2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BARX2→partner) and Y-score (partner→BARX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C20orf85 →	+0.049	+5.969	<.001	.001	3	1
BLOOD_Leukemia	IL22 →	+0.050	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	TRIM60 →	+0.039	+5.201	<.001	.006	3	1
BLOOD_Leukemia	LRRTM3 →	+0.006	+5.539	<.001	.003	3	1
BLOOD_Leukemia	KRTAP4-9 →	+0.055	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR6B1 →	+0.013	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

C20orf85 by BARX2 expression — BLOOD_Leukemia

Explore this box plot interactively →