BARX1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BARX1 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BARX1-associated genes across cancer lineages are RN7SL470P, MIR3621, and RN7SL819P. Each is linked with BARX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BARX1-to-partner and partner-to-BARX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL470P grouped by BARX1-low versus BARX1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BARX1→partner) and Y-score (partner→BARX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL470P →+0.579+4.694<.001.00131
UCECMIR3621 →+0.848+4.718<.001.00131
UCECRN7SL819P →+0.251+3.719.003.00831
UCECATP6V1G1P1 →+0.127+4.641.001.00631
UCECRNU1-14P →+0.836+4.827<.001.00131
UCECSNORD114-12 →+0.731+5.292<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

RN7SL470P by BARX1 expression — UCEC

Box plot of RN7SL470P in BARX1-low vs BARX1-high samples in UCEC.

Explore this box plot interactively →

Exploration