BARX1-DT

Across TCGA pan-cancer cohorts, BARX1-DT RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated BARX1-DT data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher BARX1-DT RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BARX1-DT expression acts as an unfavorable survival marker.

KIRC, UVM, and ACC are the cancer types where BARX1-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.470	0.673	<.001	156	view →
UVM	OS	Tertile	II,III,IV	0.309	0.709	<.001	135	view →
ACC	DFS	Tertile	All	0.155	0.607	<.001	108	view →
COAD	DFS	Tertile	All	0.696	0.814	<.001	88	view →
BRCA	OS	Tertile	All	0.876	0.940	<.001	72	view →
BLCA	DFS	Quartile	All	0.234	0.387	.002	52	view →
HNSC	DFS	Median	All	0.228	0.395	.002	38	view →
KICH	OS	Tertile	III,IV	0.162	0.808	.001	33	view →
UCS	OS	Tertile	IV	0.224	0.922	.010	30	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	24	view →
LUSC	DFS	Tertile	III,IV	0.521	0.810	.016	21	view →
LGG	DFS	Tertile	All	0.624	0.755	.014	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

BARX1-DT–KIRC (OS)

Open the KIRC breakdown →