BARX1-DT

Across TCGA pan-cancer cohorts, BARX1-DT RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of BARX1-DT’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where BARX1-DT RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BARX1-DT is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.

LUAD, BLCA, and STAD are the cancer types where BARX1-DT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BARX1-DT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	All	+0.663	<.001	8	view →
BLCA	Male	All	+0.314	.004	8	view →
STAD	All	All	−1.116	<.001	6	view →
LUSC	All	All	+0.475	<.001	5	view →
HNSC	Male	II,III,IV	+0.266	.009	4	view →
BRCA	Female	All	+0.100	.006	4	view →
PRAD	All	All	+0.018	.037	2	view →
KICH	All	All	+0.009	.009	2	view →
LIHC	Female	All	+0.008	.020	2	view →
COAD	All	III,IV	+0.052	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

BARX1-DT–LUAD

Open the LUAD breakdown →