BARHL2

Across TCGA patient cohorts, BARHL2 mutation is significantly associated with the RNA expression of many other genes, with 2,637 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BARHL2-associated genes across cancer lineages are FAM153DP, TRGV11, and CST8. Each is linked with BARHL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both BARHL2-to-partner and partner-to-BARHL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM153DP grouped by BARHL2-low versus BARHL2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BARHL2→partner) and Y-score (partner→BARHL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	FAM153DP →	+0.041	+5.033	.003	.003	3	3
CESC	TRGV11 →	+0.094	+3.996	<.001	.005	3	2
BLCA	CST8 →	+0.516	+3.959	<.001	.006	3	2
BLCA	OR2D3 →	+0.069	+3.840	<.001	.006	3	2
BRCA	RNU6-751P →	+0.127	+7.057	<.001	.009	3	2
UCEC	MIR548AL →	+0.134	+2.702	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,637 associations by consensus.

FAM153DP by BARHL2 expression — BLCA

Explore this box plot interactively →