BARHL1

Across TCGA patient cohorts, BARHL1 mutation is significantly associated with the RNA expression of many other genes, with 1,131 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BARHL1-associated genes across cancer lineages are RNU6-470P, VCY, and OR9Q2. Each is linked with BARHL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BARHL1-to-partner and partner-to-BARHL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-470P grouped by BARHL1-low versus BARHL1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BARHL1→partner) and Y-score (partner→BARHL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-470P →	+0.228	+5.748	<.001	.001	3	2
BRCA	VCY →	+0.134	+8.471	<.001	.005	3	2
COAD	OR9Q2 →	+0.030	+4.721	.004	.004	3	2
UCEC	EIF3JP1 →	+0.214	+2.257	<.001	.009	3	2
BLCA	OR2F2 →	+0.031	+5.814	<.001	.001	3	1
BLCA	RNU6-285P →	+0.379	+4.685	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,131 associations by consensus.

RNU6-470P by BARHL1 expression — LUAD

Explore this box plot interactively →