BARD1

Across TCGA patient cohorts, BARD1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,825 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BARD1-associated genes across cancer lineages are FBXO5, TTK, and TROAP. Each is linked with BARD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both BARD1-to-partner and partner-to-BARD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BARD1 versus FBXO5 in UCEC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BARD1→partner) and Y-score (partner→BARD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FBXO5 →	+1.027	+0.649	<.001	<.001	3	4
UCEC	TTK →	+1.315	+0.523	.003	.007	3	4
UCEC	TROAP →	+1.282	+0.527	.009	.004	3	4
UCEC	ZNF670-ZNF695 →	+1.047	+0.615	<.001	.002	3	4
UCEC	CCDC150 →	+1.188	+0.585	<.001	.001	3	4
GBM	SKP2 →	+0.568	+0.803	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,825 associations by consensus.

BARD1 vs FBXO5 — UCEC

Explore this scatter interactively →