BAK1

Across TCGA patient cohorts, BAK1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,902 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BAK1-associated genes across cancer lineages are CEP68, PHC1, and FBXO6. Each is linked with BAK1 in more than 4 cancer types. Because this analysis shows association rather than direction, both BAK1-to-partner and partner-to-BAK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BAK1 versus CEP68 in HNSC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAK1→partner) and Y-score (partner→BAK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CEP68 →	-0.536	-0.328	<.001	<.001	3	5
HNSC	PHC1 →	-0.432	-0.226	<.001	<.001	3	4
PDAC	FBXO6 →	+0.555	+0.444	<.001	<.001	3	4
GBM	SPATA6 →	-0.931	-0.439	<.001	<.001	3	4
COAD	LRP4 →	-1.497	-0.333	.003	.006	3	4
COAD	CTSL →	+0.805	+0.298	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,902 associations by consensus.

BAK1 vs CEP68 — HNSC

Explore this scatter interactively →