BAG3

Across TCGA patient cohorts, BAG3 RNA expression is significantly associated with the RNA expression of many other genes, with 19,661 significant associations in total. THYM shows the largest number of these associations.

The most reproducible BAG3-associated genes across cancer lineages are MCMBP, SETD7, and SAMD8. Each is linked with BAG3 in more than 31 cancer types. Because this analysis shows association rather than direction, both BAG3-to-partner and partner-to-BAG3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BAG3 versus MCMBP in DLBC, with a Pearson correlation of 0.73.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAG3→partner) and Y-score (partner→BAG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	MCMBP →	+0.974	+1.141	<.001	<.001	3	32
SCLC	SETD7 →	+1.375	+1.166	<.001	<.001	3	32
THYM	SAMD8 →	+0.982	+1.362	<.001	<.001	3	31
LAML	PLEC →	+1.233	+1.070	<.001	<.001	3	31
THYM	VCL →	+1.399	+1.319	<.001	<.001	3	31
DLBC	SLK →	+1.198	+1.220	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,661 associations by consensus.

BAG3 vs MCMBP — DLBC

Explore this scatter interactively →