BAG3

Across TCGA patient cohorts, BAG3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,434 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BAG3-associated proteins across cancer lineages are TP53BP2_S582, WASL_S430, and XRCC6_S520. Each is linked with BAG3 in more than 4 cancer types. Because this analysis shows association rather than direction, both BAG3-to-partner and partner-to-BAG3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BAG3 versus TP53BP2_S582 in PDAC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BAG3→partner) and Y-score (partner→BAG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TP53BP2_S582 →	+0.373	+0.505	<.001	.002	3	4
GBM	WASL_S430 →	-0.850	-0.833	<.001	<.001	3	4
GBM	XRCC6_S520 →	+0.953	+0.777	<.001	<.001	2	5
HNSC	RERE_S613 →	-0.412	-0.547	.004	<.001	3	4
LSCC	HK1 →	+0.312	+0.589	<.001	<.001	3	4
GBM	SCAF1_S874 →	-0.531	-0.592	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,434 associations by consensus.

BAG3 vs TP53BP2_S582 — PDAC

Explore this scatter interactively →