BAG2

Across TCGA pan-cancer cohorts, BAG2 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated BAG2 data layer compared with 25 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher BAG2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated BAG2 expression acts as an unfavorable survival marker.

UCEC, COAD, and SARC are the cancer types where BAG2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	IV	0.133	0.754	<.001	12	view →
COAD	OS	Median	All	0.105	0.669	.003	9	view →
SARC	DFS	Median	All	0.121	0.611	.041	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
SKCM	DFS	Median	All	0.216	0.613	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

BAG2–UCEC (OS)

Open the UCEC breakdown →