BAG2

Across TCGA pan-cancer cohorts, BAG2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated BAG2 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher BAG2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated BAG2 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

CCRCC, PDAC, and OV are the cancer types where BAG2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.730	0.966	.003	36	view →
PDAC	DFS	Tertile	III,IV	0.162	0.662	.003	19	view →
OV	DFS	Quartile	All	0.472	0.884	.042	8	view →
GBM	OS	Median	All	0.771	0.937	.017	2	view →
LSCC	DFS	Quartile	II,III,IV	0.888	0.187	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

BAG2–CCRCC (DFS)

Open the CCRCC breakdown →