BAG2

Across TCGA patient cohorts, BAG2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,010 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BAG2-associated genes across cancer lineages are RAB23, UCHL1, and MYL9. Each is linked with BAG2 in more than 9 cancer types. Because this analysis shows association rather than direction, both BAG2-to-partner and partner-to-BAG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BAG2 versus RAB23 in UCEC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAG2→partner) and Y-score (partner→BAG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAB23 →	+0.912	+0.867	<.001	<.001	3	10
CCRCC	UCHL1 →	+2.072	+0.667	<.001	<.001	3	8
BRCA	MYL9 →	+1.161	+0.539	<.001	<.001	3	7
HNSC	ASPN →	+1.485	+0.559	<.001	<.001	3	7
HNSC	BEND6 →	+0.751	+0.666	<.001	<.001	3	7
UCEC	MFAP5 →	+1.457	+0.471	.001	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,010 associations by consensus.

BAG2 vs RAB23 — UCEC

Explore this scatter interactively →