BAG2

Across TCGA cell cohorts, BAG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,822 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible BAG2-associated GO terms across cancer lineages are Nuclear division, Protein localization to nuclear envelope, and Nucleoside monophosphate metabolic process. Each is linked with BAG2 in more than 10 cancer types. Because this analysis shows association rather than direction, both BAG2-to-partner and partner-to-BAG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear division grouped by BAG2-low versus BAG2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BAG2→partner) and Y-score (partner→BAG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Nuclear division →	+0.097	+1.314	.002	.002	3	11
LARGE_INTESTINE	Protein localization to nuclear envelope →	+0.139	+1.455	<.001	<.001	3	10
PANCREAS	Nucleoside monophosphate metabolic process →	+0.087	+0.950	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Mitochondrial RNA metabolic process →	+0.107	+1.579	<.001	<.001	3	10
OVARY	'de novo' IMP biosynthetic process →	+0.140	+0.988	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	tRNA metabolic process →	+0.081	+1.847	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,822 associations by consensus.

Nuclear division by BAG2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →