BAD

Across TCGA patient cohorts, BAD protein abundance is significantly associated with the RNA expression of many other genes, with 7,464 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BAD-associated genes across cancer lineages are DNAJC4, MT-CYB, and RCAN1. Each is linked with BAD in more than 2 cancer types. Because this analysis shows association rather than direction, both BAD-to-partner and partner-to-BAD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BAD versus DNAJC4 in GBM, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAD→partner) and Y-score (partner→BAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DNAJC4 →	+0.466	+0.337	<.001	<.001	3	3
LUAD	MT-CYB →	+0.769	+0.201	.001	.001	3	3
BRCA	RCAN1 →	-0.725	-0.397	.003	.001	3	3
LSCC	PGD →	-0.792	-0.156	.003	.006	3	3
LSCC	MRPL49 →	+0.418	+0.250	.001	.002	3	3
LSCC	UBXN10 →	+1.311	+0.311	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,464 associations by consensus.

BAD vs DNAJC4 — GBM

Explore this scatter interactively →