BAD

Across TCGA pan-cancer cohorts, BAD RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated BAD data layer compared with 2 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher BAD RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BAD expression acts as an unfavorable survival marker, although some lineages such as ESCA and MESO show a favorable association.

ACC, UVM, and LIHC are the cancer types where BAD RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.224	0.741	<.001	79	view →
UVM	DFS	Tertile	II,III,IV	0.433	0.797	<.001	52	view →
LIHC	OS	Tertile	All	0.414	0.654	<.001	50	view →
KICH	DFS	Median	II,III,IV	0.539	1.000	.002	49	view →
LGG	OS	Quartile	All	0.359	0.648	<.001	30	view →
DLBC	DFS	Median	II,III,IV	0.477	1.000	.005	20	view →
READ	OS	Median	IV	0.497	0.879	.011	18	view →
PRAD	DFS	Quartile	All	0.696	0.915	<.001	18	view →
LAML	DFS	Median	All	0.469	0.662	.010	16	view →
HNSC	OS	Median	All	0.646	0.764	.004	15	view →
ESCA	OS	Tertile	IV	0.743	0.243	.024	15	view →
COAD	OS	Quartile	All	0.758	0.938	.020	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

BAD–ACC (DFS)

Open the ACC breakdown →