BAD

Across TCGA cell cohorts, BAD RNA expression is significantly associated with the go_rna of many other GO terms, with 3,989 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible BAD-associated GO terms across cancer lineages are Positive regulation of type B pancreatic cell development, Cellular response to nicotine, and Cellular response to platelet-derived growth factor stimulus. Each is linked with BAD in more than 18 cancer types. Because this analysis shows association rather than direction, both BAD-to-partner and partner-to-BAD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of type B pancreatic cell development grouped by BAD-low versus BAD-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BAD→partner) and Y-score (partner→BAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of type B pancreatic cell development →	+0.288	+1.357	<.001	<.001	3	19
BONE	Cellular response to nicotine →	+0.152	+0.980	.001	.001	3	14
LARGE_INTESTINE	Cellular response to platelet-derived growth factor stimulus →	+0.101	+0.736	.001	.001	3	12
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.134	+0.892	.001	<.001	3	12
LUNG_NSCLC_LUSC	Protein localization to microtubule plus-end →	+0.159	+0.722	.002	.002	3	11
LUNG_NSCLC_LUSC	Protein localization to microtubule end →	+0.159	+0.722	.002	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,989 associations by consensus.

Positive regulation of type B pancreatic cell development by BAD expression — OESOPHAGUS

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