BACH1

Across TCGA pan-cancer cohorts, BACH1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated BACH1 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher BACH1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated BACH1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LUAD, PDAC, and CCRCC are the cancer types where BACH1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.637	0.887	<.001	55	view →
PDAC	DFS	Quartile	II,III,IV	0.245	0.690	<.001	28	view →
CCRCC	OS	Median	II,III,IV	0.579	0.871	.001	16	view →
LSCC	DFS	Median	All	0.964	0.905	.032	2	view →
HNSC	DFS	Median	III,IV	0.937	1.000	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

BACH1–LUAD (OS)

Open the LUAD breakdown →