BACH1

Across TCGA patient cohorts, BACH1 mutation is significantly associated with the RNA expression of many other genes, with 4,883 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BACH1-associated genes across cancer lineages are RNA5SP492, RNA5SP222, and TRIM48. Each is linked with BACH1 in more than 2 cancer types. Because this analysis shows association rather than direction, both BACH1-to-partner and partner-to-BACH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP492 grouped by BACH1-low versus BACH1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BACH1→partner) and Y-score (partner→BACH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP492 →	+0.345	+4.056	<.001	<.001	3	3
SKCM	RNA5SP222 →	+0.093	+4.049	<.001	.007	3	3
COAD	TRIM48 →	+0.164	+4.070	<.001	.009	3	3
SKCM	NBPF5P →	+0.047	+2.627	.001	.003	3	2
COAD	RNU6-768P →	+0.555	+5.087	<.001	.002	3	2
READ	BPNT2P →	+0.148	+6.681	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,883 associations by consensus.

RNA5SP492 by BACH1 expression — CESC

Explore this box plot interactively →