BACH1-IT1

Across TCGA pan-cancer cohorts, BACH1-IT1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated BACH1-IT1 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher BACH1-IT1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated BACH1-IT1 expression acts as an unfavorable survival marker.

HNSC and UCEC are the cancer types where BACH1-IT1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.170	0.696	.010	18	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

BACH1-IT1–HNSC (DFS)

Open the HNSC breakdown →