BACH1-AS1

Across TCGA pan-cancer cohorts, BACH1-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated BACH1-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher BACH1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BACH1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and HNSC show a favorable association.

MESO, UCS, and LIHC are the cancer types where BACH1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Quartile	III,IV	0.265	0.571	.002	46	view →
UCS	DFS	Median	III,IV	0.594	0.225	.001	40	view →
LIHC	DFS	Median	All	0.461	0.620	<.001	37	view →
HNSC	DFS	Median	All	0.757	0.661	.006	36	view →
LGG	DFS	Tertile	All	0.645	0.831	<.001	35	view →
SKCM	DFS	Median	All	0.684	0.534	<.001	29	view →
BLCA	DFS	Tertile	III,IV	0.353	0.654	.004	27	view →
UVM	DFS	Quartile	All	0.286	0.778	.002	24	view →
ACC	OS	Tertile	All	0.581	0.927	.008	20	view →
KIRC	DFS	Quartile	IV	0.342	0.693	.008	18	view →
LUAD	OS	Median	III,IV	0.603	0.390	.005	17	view →
SARC	OS	Tertile	All	0.350	0.621	.003	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

BACH1-AS1–MESO (OS)

Open the MESO breakdown →