BACH1-AS1

Across TCGA pan-cancer cohorts, BACH1-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of BACH1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where BACH1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types BACH1-AS1 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, LIHC, and BRCA are the cancer types where BACH1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BACH1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−0.352	<.001	8	view →
LIHC	Female	III,IV	+0.270	.003	5	view →
BRCA	All	All	+0.268	.021	4	view →
STAD	All	All	+0.203	.014	4	view →
CHOL	All	All	+0.328	.008	1	view →
KIRC	Female	IV	−0.233	.022	1	view →
KIRC	All	All	+0.062	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 6 lineages.

BACH1-AS1–KICH

Open the KICH breakdown →