BAAT

Across TCGA patient cohorts, BAAT mutation is significantly associated with the RNA expression of many other genes, with 3,646 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAAT-associated genes across cancer lineages are WDR62, RN7SL134P, and XPNPEP1. Each is linked with BAAT in more than 2 cancer types. Because this analysis shows association rather than direction, both BAAT-to-partner and partner-to-BAAT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WDR62 grouped by BAAT-low versus BAAT-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAAT→partner) and Y-score (partner→BAAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WDR62 →	+0.493	+2.928	<.001	<.001	3	3
UCEC	RN7SL134P →	+0.093	+1.955	<.001	.001	3	3
UCEC	XPNPEP1 →	+0.441	+1.893	<.001	<.001	3	3
SKCM	BAALC →	-1.811	-2.415	<.001	.003	3	3
BRCA	RNU6-1299P →	+0.328	+4.721	<.001	.007	3	2
UCEC	COX15 →	+0.400	+3.860	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,646 associations by consensus.

WDR62 by BAAT expression — UCEC

Explore this box plot interactively →