BAAT

Across TCGA pan-cancer cohorts, BAAT RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of BAAT’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where BAAT RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BAAT is over-expressed in tumor, although a few such as CHOL and LUSC show the opposite, repressed pattern.

COAD, KIRC, and STAD are the cancer types where BAAT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BAAT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.436	<.001	10	view →
KIRC	All	All	+1.114	<.001	9	view →
STAD	All	All	+0.864	.003	8	view →
READ	All	All	+0.311	<.001	5	view →
CHOL	Male	All	−4.045	<.001	4	view →
LUSC	Male	II,III,IV	−1.038	<.001	4	view →
LUAD	All	All	+0.575	.005	4	view →
THCA	All	All	−0.032	.003	3	view →
ESCA	All	II,III,IV	+0.494	.018	2	view →
KICH	Female	All	−0.130	.029	1	view →
KIRP	Male	All	−0.110	.028	1	view →
HNSC	Male	III,IV	+0.055	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

BAAT–COAD

Open the COAD breakdown →