BAAT

Across TCGA patient cohorts, BAAT mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAAT-associated genes across cancer lineages are INPP4B, p62 Lck ligand, and STAT3_pY705. Each is linked with BAAT in more than 1 cancer types. Because this analysis shows association rather than direction, both BAAT-to-partner and partner-to-BAAT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by BAAT-low versus BAAT-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAAT→partner) and Y-score (partner→BAAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.314	-3.906	.003	<.001	3	2
UCEC	p62 Lck ligand →	+0.360	+2.222	<.001	.009	3	2
UCEC	STAT3_pY705 →	-0.234	-1.321	.007	.029	3	2
UCEC	Caspase-7-cleavedD198 →	+0.515	+1.434	.009	.027	3	2
UCEC	Caspase-8 →	-0.256	-2.201	.002	<.001	3	2
SKCM	eEF2 →	+0.312	+2.321	.025	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

INPP4B by BAAT expression — UCEC

Explore this box plot interactively →