BAAT

Across TCGA cell cohorts, BAAT mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible BAAT-associated genes across cancer lineages are WFDC11, C3orf22, and GOLGA6L22. Each is linked with BAAT in more than 1 cancer types. Because this analysis shows association rather than direction, both BAAT-to-partner and partner-to-BAAT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WFDC11 grouped by BAAT-low versus BAAT-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAAT→partner) and Y-score (partner→BAAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	WFDC11 →	+0.104	+4.977	<.001	.007	3	1
SKIN	C3orf22 →	+0.079	+5.415	<.001	.004	3	1
SKIN	GOLGA6L22 →	+0.006	+6.022	<.001	.001	3	1
LUNG_SCLC	OR8B12 →	+0.032	+5.029	<.001	.006	3	1
LARGE_INTESTINE	CFHR2 →	+0.032	+3.700	<.001	.009	3	1
SKIN	TLR8 →	+0.020	+5.614	<.001	.002	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

WFDC11 by BAAT expression — SKIN

Explore this box plot interactively →