B4GALT5

Across TCGA patient cohorts, B4GALT5 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GALT5-associated genes across cancer lineages are Ku80, MEK1, and MSH2. Each is linked with B4GALT5 in more than 1 cancer types. Because this analysis shows association rather than direction, both B4GALT5-to-partner and partner-to-B4GALT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by B4GALT5-low versus B4GALT5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALT5→partner) and Y-score (partner→B4GALT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.314	+2.183	.011	.035	3	1
UCEC	MEK1 →	+0.499	+3.169	.009	.019	3	1
UCEC	MSH2 →	-0.387	-2.973	.001	.035	3	1
UCEC	PEA-15_pS116 →	+0.577	+3.321	.001	.010	3	1
UCEC	PI3K-p110-a →	-0.192	-3.321	.037	.010	3	1
UCEC	Rab25 →	-0.377	-3.321	.030	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Ku80 by B4GALT5 expression — UCEC

Explore this box plot interactively →