B4GALT5

Across TCGA pan-cancer cohorts, B4GALT5 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated B4GALT5 data layer compared with 3 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher B4GALT5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated B4GALT5 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SCLC show a favorable association.

PAAD, ACC, and LIHC are the cancer types where B4GALT5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	DFS	Median	All	0.159	0.385	<.001	78	view →
ACC	DFS	Median	All	0.239	0.666	<.001	68	view →
LIHC	OS	Median	All	0.401	0.626	<.001	63	view →
BLCA	OS	Median	II,III,IV	0.544	0.669	.007	46	view →
LGG	OS	Median	All	0.757	0.870	<.001	40	view →
MESO	DFS	Tertile	All	0.259	0.669	.012	40	view →
KIRC	DFS	Quartile	IV	0.910	0.347	<.001	38	view →
UVM	DFS	Median	III,IV	0.280	0.576	.016	29	view →
SARC	DFS	Median	All	0.215	0.540	<.001	29	view →
SCLC	DFS	Quartile	All	0.603	0.258	.001	27	view →
OV	OS	Tertile	All	0.270	0.376	.006	16	view →
HNSC	DFS	Tertile	IV	0.462	0.219	.001	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

B4GALT5–PAAD (DFS)

Open the PAAD breakdown →